BK-virus (BKV) – structure, epidemiology and pathogenesis
نویسندگان
چکیده
منابع مشابه
Correlates of quantitative measurement of BK polyomavirus (BKV) DNA with clinical course of BKV infection in renal transplant patients.
BK virus-allograft nephropathy (BKVAN) is an increasingly recognized complication after kidney transplantation. Quantitative tests have been advocated to monitor patients, but data demonstrating their efficacy are relatively limited. We developed a real-time PCR assay to quantitate BK virus loads in the setting of renal transplantation, and we correlated the BK virus load with clinical course a...
متن کاملThe role of BK virus in acute respiratory tract disease and the presence of BKV DNA in tonsils.
The significance of BKV infections relative to infections by generally tested respiratory agents was investigated in children with acute respiratory disease. Paired sera from 177 children admitted to a hospital for acute respiratory disease were tested for significant rises in antibodies. Sera from seven patients showed a seroconversion to BKV and clinical signs of acute upper respiratory tract...
متن کاملEarly BK polyomavirus (BKV) reactivation in donor kidney is a risk factor for development of BKV-associated nephropathy.
The pathogenesis of BK polyomavirus (BKV) infection and associated nephropathy in renal transplant recipients is not clearly understood. To gain insight, urine and plasma samples were collected from 112 renal transplant recipients before and after transplantation and tested for the presence of BKV by polymerase chain reaction. Detection of BKV infection very early (ie, 5 days) after transplanta...
متن کاملبررسی مولکولی فعالیت مجدد ویروس BK در ادرار بیماران پیوند کلیه
Background & Amis: BK polyomavirus (BKV) is common infection of childhood that persists in kidney epithelium. BKV reactivation characterized by viruria occurs in 35% to 57% of renal allograft recipients. BK virus was detected in serum samples in 6% to 29% of these patients. BKV-associated nephropathy occurs in as many as 8% of renal allograft recipients and may lead to . This study was carri...
متن کاملBK Viremia among Iranian Renal Transplant Candidates
Background: Primary infection with BK virus (BKV) is occurred during childhood and usually asymptomatic, but after initial infection, BKV may persist lifelong in the kidney and genitourinary tract. Reactivation may occur in individuals with compromised immunity such as renal transplant recipients. Due to the role of BKV in BK virus-associated nephropathy (BKVAN) and po...
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ژورنال
عنوان ژورنال: Journal of Pre-Clinical and Clinical Research
سال: 2014
ISSN: 1898-2395,1898-7516
DOI: 10.26444/jpccr/71444